Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FAS1 Polyclonal antibody

Uniprot No.

Q9SXY0

Target Names

FAS1

Alternative Names

FAS1 antibody; NFB2 antibody; At1g65470 antibody; F5I14.2 antibody; T8F5.24Chromatin assembly factor 1 subunit FAS1 antibody; CAF-1 subunit FAS1 antibody; CAF-1 p150 homolog antibody; Protein FASCIATA 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana FAS1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Component of the chromatin assembly factor complex (CAF-1) involved in chromatin assembly following DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. Required for several aspects of development, including seedling growth and leaf hair differentiation. Plays a critical role in the organization of shoot apical meristem (SAM) and root apical meristem (RAM) during postembryonic development by facilitating stable maintenance of gene expression states. Seems not required to maintain transcriptional repression of heterochromatic genes. Involved in heterologous recombination. May repress endocycle.

Gene References into Functions

CAF-1 ensures the stable inheritance of epigenetic states through growth and development in Arabidopsis PMID: 16436052
required in vitro for nucleosome assembly onto newly replicated chromatin in human cells and Arabidopsis thaliana PMID: 16980538
Depletion of FAS1 increased the frequency of somatic homologous recombination (HR) in planta approximately 40-fold. PMID: 17110925
The FASCIATA1 (FAS1) gene, which encodes the CAF-1 large subunit, is a target of E2F transcription factors. PMID: 17351056
Loss of activity of the Chromatin assembly factor 1 (CAF1) pathway causes delay and arrest of the cell cycle during pollen development but does not alter cell fate. [CAF1] PMID: 18045841
CAF-1 is required for cell differentiation and regulates trichome development together with STICHEL in an endoreduplication-independent pathway.[CAF-1] PMID: 18477400

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Subcellular Location

Nucleus.

Protein Families

CHAF1A family

Tissue Specificity

Expressed in the shoot apical meristem, young leaf primordia, root tip and first lateral root primordium at the hypocotyl/root junction.

Database Links

KEGG: ath:AT1G65470

STRING: 3702.AT1G65470.1

UniGene: At.20487

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FAS1 Antibody

Product Details

Customer Reviews and Q&A

Target Background