Fib Antibody

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Code	CSB-PA814174XA01DLK
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Product Details

Full Product Name

Rabbit anti-Drosophila erecta (Fruit fly) Fib Polyclonal antibody

Uniprot No.

Q8I1F4

Target Names

Fib

Alternative Names

Fib antibody; GG20072rRNA 2'-O-methyltransferase fibrillarin antibody; EC 2.1.1.- antibody; Histone-glutamine methyltransferase antibody

Raised in

Rabbit

Species Reactivity

Drosophila erecta (Fruit fly)

Immunogen

Recombinant Drosophila erecta (Fruit fly) Fib protein

Immunogen Species

Drosophila erecta (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus.

Subcellular Location

Nucleus, nucleolus.

Protein Families

Methyltransferase superfamily, Fibrillarin family

Database Links

KEGG: der:Dere_GG20072

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Phage Display Service

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Protein Service

Gene Synthesis Service

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Fib Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background