Fsn Antibody

Code CSB-PA893237XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Fsn Polyclonal antibody
Uniprot No.
Target Names
Fsn
Alternative Names
Fsn antibody; CG4643F-box/SPRY domain-containing protein 1 antibody; DFsn antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Fsn protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ). Negatively regulates the localization of vas to the posterior pole of the oocyte. Involved in primordial germ cell formation.
Gene References into Functions
  1. The F-box protein DFsn binds the ubiquitin ligase Highwire and is required to down-regulate the levels of the Wallenda/DLK kinase and restrain synaptic terminal growth. PMID: 17697379
Subcellular Location
Cytoplasm. Nucleus. Cell junction, synapse. Cell projection, axon. Perikaryon.
Protein Families
FBXO45/Fsn family
Tissue Specificity
Expressed in nurse cells and oocytes (at protein level). Expressed in the brain. Expressed in the neuromuscular junction (NMJ).
Database Links

KEGG: dme:Dmel_CG4643

STRING: 7227.FBpp0086875

UniGene: Dm.21576

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