fem-2 Antibody

Code CSB-PA239360XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans fem-2 Polyclonal antibody
Uniprot No.
Target Names
fem-2
Alternative Names
fem-2 antibody; T19C3.8Protein phosphatase fem-2 antibody; EC 3.1.3.16 antibody; Ca(2+)/calmodulin-dependent protein kinase phosphatase antibody; CaM-kinase phosphatase antibody; CaMKPase antibody; Feminization of XX and XO animals protein 2 antibody; Sex-determining protein fem-2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans fem-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Dephosphorylates auto-phosphorylated Ca(2+)/calmodulin-dependent protein kinase unc-43/CAMKII in vitro. Involved in the regulation of sex determination. Together with fem-3, required for male sexual development by promoting the proteasomal-mediated degradation of tra-1, a transcription repressor of male-specific genes. Promotes apoptosis.
Gene References into Functions
  1. Results indicate that the N-terminal domain (NTD) works in mediating the sex-determining role of FEM-1/2/3 complex. PMID: 23760267
Protein Families
PP2C family
Database Links

KEGG: cel:CELE_T19C3.8

STRING: 6239.T19C3.8

UniGene: Cel.7385

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