fft3 Antibody

1. Data indicate Fun30(Fft3) as a chromatin remodeller, which localizes at transcribing regions to promote RNA polymerase II (RNAPII) transcription. PMID: 28218250
2. These analyses of the regulation of nucleosome dynamics by Fun30(Fft3) during RNA polymerase II (RNAPII) -mediated transcription reveal an unprecedented role for a chromatin remodeler in nucleosome disassembly at transcribing regions. They offer a new conceptual framework that can describe, in mathematical terms, how nucleosome dynamics are controlled during RNAPII-mediated elongation. PMID: 28925811
3. This work uncovers a conserved factor critical for epigenetic inheritance of heterochromatin and describes a mechanism in which Fft3 suppresses nucleosome turnover, preventing formation of structural barriers that impede replication at fragile regions in the genome. PMID: 28318821
4. We propose that Fft3 has a global role in mediating association between specific chromatin domains and the nuclear envelope PMID: 25798942
5. Fft3 controls the identity of chromatin domains by protecting these regions from euchromatin assembly. PMID: 21437270
6. Results indicate that Snf2SR is involved in the Ran GTPase cycle in vivo. PMID: 18422602

Show More

Hide All

KEGG: spo:SPAC25A8.01c

STRING: 4896.SPAC25A8.01c.1