FIP37 Antibody

Code CSB-PA437279XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FIP37 Polyclonal antibody
Uniprot No.
Target Names
FIP37
Alternative Names
FIP37 antibody; At3g54170 antibody; F24B22.130FKBP12-interacting protein of 37 kDa antibody; FIP-37 antibody; Immunophilin-interacting protein AtFIP37 antibody; Protein WTAP homolog antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana FIP37 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable regulatory subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs. Associates with MTA, MTB, VIR and HAKAI to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences. N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing. Essential protein required during endosperm development and embryogenesis. Involved in endoreduplication, especially in trichomes. May play a role in splicing events.
Gene References into Functions
  1. Results show an essential function for N6-methyladenosine in a multicellular eukaryote, and the interaction with At FIP37 suggests possible RNA processing events that might be regulated or altered by this base modification. PMID: 18505803
Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm.
Protein Families
Fl(2)d family
Tissue Specificity
Ubiquitously expressed with higher levels in primary and lateral roots, leaves, trichomes, and in pollen grains (at protein level).
Database Links

KEGG: ath:AT3G54170

STRING: 3702.AT3G54170.1

UniGene: At.930

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