fitm-2 Antibody

Code CSB-PA688566XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans fitm-2 Polyclonal antibody
Uniprot No.
Target Names
fitm-2
Alternative Names
fitm-2; fit2; fitm2; ZK265.9; Acyl-coenzyme A diphosphatase FITM2; FIT family protein fitm-2; Fat storage-inducing transmembrane homolog 2; Fat storage-inducing transmembrane protein 2; Fat-inducing protein 2
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans fitm-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology, ER morphology and cytoskeletal organization.
Gene References into Functions
  1. This paper denotes this gene as Fit2 (fat-inducing transcript 2), which is evolutionarily well-conserved. PMID: 18160536
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
FIT family
Database Links

KEGG: cel:CELE_ZK265.9

UniGene: Cel.16148

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