FKBP65 Antibody

Code CSB-PA872253XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FKBP65 Polyclonal antibody
Uniprot No.
Target Names
FKBP65
Alternative Names
FKBP65 antibody; ROF2 antibody; At5g48570 antibody; K15N18.12Peptidyl-prolyl cis-trans isomerase FKBP65 antibody; PPIase FKBP65 antibody; EC 5.2.1.8 antibody; 70 kDa peptidyl-prolyl isomerase antibody; FK506-binding protein 65 antibody; AtFKBP65 antibody; Immunophilin FKBP65 antibody; Peptidyl-prolyl isomerase ROF2 antibody; Protein ROTAMASE FKBP 2 antibody; Rotamase antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana FKBP65 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Co-chaperone that negatively modulates thermotolerance by interacting with FKBP62 and decreasing the HSFA2-mediated accumulation of chaperones of the small-HSPs family. Plays a positive role in tolerance to intracellular acid stress by maintaining the pH homeostasis. May be a part of transcription regulation pathways upon pathogen infection.
Gene References into Functions
  1. secondary structure of the ROF2 protein PMID: 23996408
  2. Data show that over-expression of peptidyl-prolyl cis-trans isomerase (ROF2) activates K(+) uptake, causing depolarization of the plasma membrane, which activates the electrogenic H(+) pump. PMID: 22268595
  3. Data demonstrates that ROF2 participates in long term acquired thermotolerance. ROF2 was a heat stress modulator which functions in negative feedback regulation of HsfA2. [ROF2] PMID: 19876748
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
FKBP-type PPIase family
Tissue Specificity
Expressed in the whole plant.
Database Links

KEGG: ath:AT5G48570

STRING: 3702.AT5G48570.1

UniGene: At.29841

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