FKS1 Antibody

Code CSB-PA330907XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) FKS1 Polyclonal antibody
Uniprot No.
Target Names
FKS1
Alternative Names
FKS1 antibody; CND1 antibody; CWH53 antibody; ETG1 antibody; GLS1 antibody; GSC1 antibody; PBR1 antibody; YLR342W antibody; L8300.61,3-beta-glucan synthase component FKS1 antibody; EC 2.4.1.34 antibody; 1,3-beta-D-glucan-UDP glucosyltransferase antibody; Calcineurin dependent protein 1 antibody; Calcofluor white hypersensitivity protein 53 antibody; Echinocandin target gene protein 1 antibody; FK506 sensitivity protein 1 antibody; Glucan synthase of cerevisiae protein 1 antibody; Papulacandin B resistance protein 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) FKS1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Alternate catalytic subunit of the 1,3-beta-glucan synthase (GS). Synthesizes 1,3-beta-glucan, a major structural component of the yeast cell wall. Involved in cell wall synthesis, maintenance and cell wall remodeling.
Gene References into Functions
  1. the mitotic spindle breakage observed in endocytosis mutants can be rescued either by deleting or inhibiting the activities of, CHS2, CHS3 and FKS1, which are involved in septum formation. The findings from our study highlight the importance of timely endocytosis of cytokinetic enzymes at the division site in safeguarding mitotic spindle integrity during mitotic exit. PMID: 27447488
  2. Both the N terminus and the C terminus are essential for Fks1 function. PMID: 22581527
  3. Fks1p consists of multiple domains that are required for cell wall construction and cellular morphogenesis. PMID: 20124029
Subcellular Location
Mitochondrion. Cell membrane; Multi-pass membrane protein. Note=Localizes to the sites of polarized growth. Colocalizes with cortical actin patches and moves on the cell surface at the sites of cell wall remodeling. Actin patch motility is required for the movement. Early at the cell cycle, localizes at the presumed bud site of the mother cell and at the tip of the small bud. As the bud enlarges, appears as discernible spots in the medium-sized bud and these spots colocalize with actin patches. Late in the cell cycle, disappears in large budded cells, while the actin patches disperse over the cell. During cytokinesis, is concentrated in the neck, overlapping with the location of cortical actin patches.
Protein Families
Glycosyltransferase 48 family
Database Links

KEGG: sce:YLR342W

STRING: 4932.YLR342W

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