fliC Antibody

1. Our results provide proof-of-principle demonstration that a reengineered hybrid FliC could be used as a platform for polymeric subunit vaccines, enhancing T cell-dependent and possibly inducing T-independent antibody responses from B-1 B cells as well. PMID: 26265529
2. Data indicate the biological activity of a TLR5:flagellin complex with a 2:2 stoichiometry. PMID: 23624387
3. the NAIP5-NLRC4 inflammasome is induced by direct interactions with conserved N- and C-terminal regions of flagellin PMID: 23012363
4. These findings established the signaling pathway mediating the chemokine induction activity of LL-37 in primary keratinocytes and the synergistic effect of LL-37 on the cell response to flagellin. PMID: 22516952
5. A flagellin mutant deprived of the complete D3 domain (DeltaD3_FliC) exhibited a significantly decreased thermal stability (T(m) 41.9 degrees C) as compared to intact flagellin (T(m) 47.3 degrees C). PMID: 20868693
6. Nonsurgical intratracheal instillation of 1 microg of purified, recombinant flagellin in several strains of mice stimulated a transient innate immune response in the lung PMID: 15501801
7. Repression of expression of antigens such as FliC by intracellular Salmonella facilitates evasion of adaptive immune recognition by murine CD4+ T cells. PMID: 15944299
8. The role of fliC in the induction of inflammatory reactions and apoptosis of gastrointestinal epithelial cells is reported. PMID: 16179598
9. Salmonella transcribed fliC in the Peyer's Patches but not in the mesenteric lymph nodes and spleen PMID: 16803592
10. mRNAs for types B and C flagellin compete for occupancy of a site that directs the product toward assembly and FljA influences this competition PMID: 16844786
11. Activated NF-kappab contributes to gene expr3erssion lf flic. PMID: 17292856

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KEGG: stm:STM1959

STRING: 99287.STM1959