fliI Antibody

Code CSB-PA630500XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) fliI Polyclonal antibody
Uniprot No.
Target Names
fliI
Alternative Names
fliI antibody; CG1484Protein flightless-1 antibody; Flightless-I antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) fliI protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May play a key role in embryonic cellularization by interacting with both the cytoskeleton and other cellular components. Alternatively, it may play a structural role in indirect flight muscle. Vital for embryonic development.
Gene References into Functions
  1. The results showed that Drosophila FliI regulates the expression of metabolic genes, and that dysregulation of the transcription controlled by FliI gives rise to metabolic stress and problems in the development and physiology of Drosophila. PMID: 30060781
  2. effect of FliI protein on actin remodelling is a vital part of cellular motility, contraction and adhesion. Exact signaling pathways and mechanisms underpinning FliI effects in wound healing are yet to be fully identified[review] PMID: 17526423
  3. Drosophila flightless-I gene, highly conserved in C. elegans and humans, is involved in gastrulation and muscle degeneration PMID: 8248259
Protein Families
Villin/gelsolin family
Tissue Specificity
Found in ovaries, larval fat bodies, brain and adult thorax.
Database Links

KEGG: dme:Dmel_CG1484

STRING: 7227.FBpp0076893

UniGene: Dm.1666

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