fwe Antibody

Datasheet

Code	CSB-PA836120XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) fwe Polyclonal antibody

Uniprot No.

Q95T12

Target Names

fwe

Alternative Names

fwe; flower; CG6151; Calcium channel flower; 3L5

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) fwe protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis. Isoform A and isoform B are mainly required in the nervous system and necessary in photoreceptor cells.

Gene References into Functions

Fwe promotes clathrin-mediated endocytosis independently of Ca2+channeling. PMID: 28414717
Our results suggest that Fwe is a component of the cell competition response that is required and sufficient to label cells as "winners" or "losers.". PMID: 20627080
Study reports the identification of a protein that has not been previously characterized in any species and whose loss affects endocytosis. It contains three or four transmembrane domains and is associated with synaptic vesicles. PMID: 19737521

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.

Protein Families

Calcium channel flower family

Tissue Specificity

Isoform B is expressed in the neuropils of embryonic, larval, adult CNS, and R1-R6 terminals. Expression in the central nervous system (CNS) starts at embryonic stage 13.

Database Links

KEGG: dme:Dmel_CG6151

STRING: 7227.FBpp0075297

UniGene: Dm.4008

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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fwe Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background