FLR1 Antibody

Code CSB-PA327784XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) FLR1 Polyclonal antibody
Uniprot No.
Target Names
FLR1
Alternative Names
FLR1 antibody; YBR008C antibody; YBR0120Fluconazole resistance protein 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) FLR1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable efflux transporter. Confers resistance to the azole derivative fluconazole (FCZ).
Gene References into Functions
  1. Yap1-mediated canthin-6-one resistance involves the plasma membrane major-facilitator superfamily efflux pump Flr1, but not the vacuolar ATP-binding-cassette transporter Ycf1. PMID: 23912082
  2. An S-system formalism was used to model the interactions of a five-gene network encoding four transcription factors (Yap1, Yrr1, Rpn4 and Pdr3) regulating the transcriptional activation of the FLR1 gene. PMID: 21976379
  3. Data suggest that expression of FLR1 can be regulated by phospholipase C, a component of a signal transduction pathway, and by Mediator, a general transcription factor. PMID: 16352614
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Major facilitator superfamily
Database Links

KEGG: sce:YBR008C

STRING: 4932.YBR008C

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