for3 Antibody

Code CSB-PA527222XA01SXV
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Product Details

Full Product Name
Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) for3 Polyclonal antibody
Uniprot No.
Target Names
for3
Alternative Names
for3 antibody; SPCC895.05Formin-3 antibody
Raised in
Rabbit
Species Reactivity
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen
Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) for3 protein
Immunogen Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization.
Gene References into Functions
  1. Cdc12 and for3 cooperate in cytokinesis and de novo actin assembly at the division site is predominant for contractile ring formation. PMID: 24127216
  2. For3 nucleates filaments 100-fold less well than Fus1, but like Cdc12, processively elongates profilin-actin at a moderate rate and lacks filament-bundling activity. PMID: 21865598
  3. For3p localizes to small dots that appear transiently at cell tips and then move away on actin cables dependent on the continuous assembly of actin in cables. PMID: 16782006
  4. Results indicate that Rga4p functionally interacts with For3p and has a novel function in the control of cell diameter and cell growth. PMID: 17377067
  5. flow of actin cables may establish actin and For3p concentration gradients in the cytoplasm that could be important in global cell patterning. PMID: 19116660

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Subcellular Location
Cell membrane; Peripheral membrane protein. Note=Found at the cell periphery and the growing tips of interphase cells. Localized to the septum region during cell division and upon cell division begins to localize to the new end, with some remaining at the older end.
Protein Families
Formin homology family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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