FOXN4 Antibody

Code CSB-PA832936XA01DIL
Product Type Polyclonal Antibody
Uniprot No. A2BGM5
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) FOXN4 protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Forkhead box protein N4 foxn4 sli slipjig
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names foxn4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal.
Subcellular Location Nucleus
Tissue Specificity Isoform 1 is expressed mainly in adult thymus. Isoform 2 is detected in adult skin. Isoform 3 is expressed in adult brain and embryo. Prominent expression sites include the olfactory placode, the basal layer of the olfactory epithelium, the neuroepitheliu
Database Links

KEGG: dre:30315

STRING: 7955.ENSDARP00000020367

UniGene: Dr.81266

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