mutM Antibody

Code CSB-PA482642XA01EOK
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O45:K1 (strain S88 / ExPEC) mutM Polyclonal antibody
Uniprot No.
Target Names
mutM
Alternative Names
mutM antibody; fpg antibody; ECS88_4049 antibody; Formamidopyrimidine-DNA glycosylase antibody; Fapy-DNA glycosylase antibody; EC 3.2.2.23 antibody; DNA-(apurinic or apyrimidinic site) lyase MutM antibody; AP lyase MutM antibody; EC 4.2.99.18 antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli O45:K1 (strain S88 / ExPEC)
Immunogen
Recombinant Escherichia coli O45:K1 (strain S88 / ExPEC) mutM protein
Immunogen Species
Escherichia coli O45:K1 (strain S88 / ExPEC)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Protein Families
FPG family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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