FH Antibody

Code CSB-PA584539XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FH Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
FH antibody; At4g03240 antibody; F4C21.17 antibody; Frataxin antibody; mitochondrial antibody; Fxn antibody; EC antibody
Raised in
Species Reactivity
Arabidopsis thaliana
Recombinant Arabidopsis thaliana FH protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. Binds to the mitochondrial cysteine desulfurase NIFS1 and increases its activity.
Gene References into Functions
  1. Frataxin deficiency alters the normal functioning of chloroplasts by affecting the levels of Fe, chlorophyll, and the photosynthetic electron transport chain in this organelle. PMID: 26517126
  2. AtFH, apart from its role in protecting bioavailable iron within mitochondria and the biogenesis of Fe-S groups, also plays a role in the biosynthesis of heme groups in plants. PMID: 21166997
  3. These results indicate that frataxin is an essential protein in plants, required for full activity of mitochondrial Fe-S proteins and playing a protective role against oxidative damage. [frataxin] [ATFH] PMID: 17092311
  4. findings suggest a key role of plant frataxin during embryogenesis PMID: 17258206
  5. Frataxin deficiency leads also to nitric oxide (NO) accumulation in both, atfh-1 roots and frataxin null mutant yeast PMID: 19114041

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Subcellular Location
Protein Families
Frataxin family
Database Links

KEGG: ath:AT4G03240

STRING: 3702.AT4G03240.1

UniGene: At.50317

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