fry Antibody

Code CSB-PA895654XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) fry Polyclonal antibody
Uniprot No.
Target Names
fry
Alternative Names
fry antibody; CG32045 antibody; Protein furry antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) fry protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a role in the Trc/fry signaling pathway by promoting trc kinase activity. Plays a key role in maintaining the integrity of polarized cell extensions (arista) during morphogenesis, regulates the actin cytoskeleton. Plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. Together with trc, has a role in regulating microtubule-sliding during neurite outgrowth.
Gene References into Functions
  1. Full length Fry and Trc show only partial co-localization in growing bristles while an amino terminal fragment of Fry shows close to complete co-localization with Trc suggests that the interaction between these proteins is transient and regulated. PMID: 20406475
  2. trc is regulated by phosphorylation and interacts with fry during wing hair development. PMID: 15591127
Protein Families
Furry protein family
Tissue Specificity
Co-expressed with trc in all da neurons in third instar wild-type larvae; axons and dendritic branches.
Database Links

KEGG: dme:Dmel_CG32045

STRING: 7227.FBpp0297352

UniGene: Dm.1919

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