fs(1)h Antibody

Code CSB-PA319578XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) fs(1)h Polyclonal antibody
Uniprot No.
Target Names
fs(1)h
Alternative Names
fs(1)h antibody; fsh antibody; CG2252Homeotic protein female sterile antibody; Fragile-chorion membrane protein antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) fs(1)h protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required maternally for proper expression of other homeotic genes involved in pattern formation, such as Ubx.
Gene References into Functions
  1. Consistent with the independent modes of CncC regulation by Keap1 and Fs(1)h, combinations of drugs that can specifically target these pathways cause a strong synergistic and specific activation of protective CncC- dependent gene expression and boosts oxidative stress resistance. PMID: 27233051
  2. Inhibition of FSH-binding to chromatin resulted in global down-regulation of transcription. FSH biochemically interacts with ASH1. PMID: 23442797
  3. The results indicate that the two Fs(1)h isoforms have different binding profiles, with the short isoform binding at promoters and enhancers. PMID: 23945939
  4. the small isoform of fs(1)h acts as a critical component of a regulatory circuitry mediating long-range effects of distant enhancers. PMID: 17526731
  5. data link Ras signaling with modulation of a chromatin-binding transcription factor, Fs(1)h, suggesting a novel mechanism by which Ras can modulate gene expression PMID: 18264999

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Subcellular Location
Membrane; Multi-pass membrane protein.
Database Links

KEGG: dme:Dmel_CG2252

STRING: 7227.FBpp0305499

UniGene: Dm.7909

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