ftnA Antibody

Code CSB-PA359266XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) ftnA Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
ftnA antibody; ftn antibody; gen-165 antibody; rsgA antibody; b1905 antibody; JW1893Bacterial non-heme ferritin antibody; EC 1.16.3.2 antibody; Ferritin-1 antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
A synthesized peptide derived from Escherichia coli (strain K12) ftnA protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, Dot blot (guaranteed specific to the immunizing peptide)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
①. 100ug * KLH-conjugated peptide paired with 100ug * BSA-conjugated peptide (positive control);
②. 1ml*pre-immune serum (used as negative control) for free;
③. Rabbit polyclonal antibodies purified by Antigen Affinity;
Quality Guarantee
1. CUSABIO guarantees the antibody purity > 95% confirmed by SDS-PAGE.
2. CUSABIO guarantees the antibody titer > 1: 64,000 confirmed by ELISA.
3. CUSABIO guarantees to offer Peptide-specific Dot blot.
4. CUSABIO guarantees 100% risk-free: No qualified antibody, no charge.
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Iron-storage protein.
Gene References into Functions
  1. Here, the authors show evidence for a short path for iron uptake from His93 on the surface to the ferroxidase center in Helicobacter pylori ferritin and Escherichia coli ferritin. PMID: 27777002
  2. the data indicate that there are multiple iron-oxidation pathways in EcFtnA with O2 and H2O2 as oxidants. PMID: 24380371
  3. results show that ftnA iron induction is independent of RyhB and instead involves direct interaction of Fe(2+)-Fur with an 'extended' Fur binding site (containing five tandem Fur boxes) located upstream (-83) of the ftnA promoter. PMID: 20015147
  4. isothermal titration calorimetric equations describing a binding model for three classes of independent binding sites are reported here for the first time PMID: 16229472
  5. E. coli FtnA may act as an iron buffer to sequester the iron released from the disrupted iron-sulfur clusters under oxidative stress conditions and to facilitate the re-assembly of the disrupted iron-sulfur clusters under normal physiological conditions. PMID: 18618270

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Subcellular Location
Cytoplasm.
Protein Families
Ferritin family, Prokaryotic subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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