ftz-f1 Antibody

1. the alpha6 helix is dynamic in solution when Ftz-F1 is bound to the LxxLL motif of its cofactor Ftz, undergoing motions on the fast (picosecond to nanosecond) as well as slow (microsecond to millisecond) time scales. PMID: 29547262
2. a novel ecdysone-dependent enhancer in the intron of ftz-f1 gene PMID: 28726107
3. Comparative analysis of enhancers containing Ftz/Ftz-F1 binding sites that were or were not bona fide targets in vivo suggested that GAF negatively regulates enhancers that contain Ftz/Ftz-F1 binding sites but are not actually utilized. PMID: 27723822
4. dATAC histone acetyltransferase complex is indispensable for the regulation of expression and probably for the stabilization of Ftz-F1, the main transcription regulator of Halloween genes. PMID: 25959239
5. betaFTZ-F1 is expressed in most cells at the late pupal stage, under the control of ecdysteroids and plays important roles during pupal development. PMID: 24611773
6. functional equivalence of ftz-f1 orthologs in these sensitive in vivo assays argues against specific activating ligands for NR5A family members PMID: 23340581
7. ssFTZ-F1 is required for fat-body remodeling in Drosophila PMID: 21978772
8. betaFTZ-F1 is a regulator for temporal gene expression at the onset of metamorphosis PMID: 12392575
9. betaFTZ-F1 plays a role in regulating ecdysteroid titers during post-embryonic developmentby regulating Phantom protein and Disembodied protein expression. PMID: 15936331
10. EDG84A gene encoding pupal cuticle protein is one of the targets of ecdysteroid-inducible transcription factor betaFTZ-F1; betaFTZ-F1 is expressed in almost all tissues. PMID: 16025347
11. Serves as a molecular sign to guide the recruitment of ecdysone receptor/Ultraspiracle/FISC to 20-hydroxyecdysone-inducible target promoters. PMID: 17015464
12. propose that pair-rule genes, exemplified by Ftz/Ftz-F1, promote segmentation by acting at different hierarchical levels, regulating segmentation and regulatory genes PMID: 19679121
13. The Ftz-F1 DNA binding domain interacts strongly with Ftz and dramatically facilitates the binding of Ftz to target DNA. PMID: 11520662

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KEGG: dme:Dmel_CG4059

STRING: 7227.FBpp0074853

UniGene: Dm.995