nac Antibody

Code CSB-PA893760XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) nac Polyclonal antibody
Uniprot No.
Target Names
nac
Alternative Names
nac antibody; Gfr antibody; CG9620GDP-fucose transporter 1 antibody; Neuronally altered carbohydrate antibody; Solute carrier family 35 member C1 homolog antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) nac protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling.
Gene References into Functions
  1. the nac(1) Gfr mutation produces a previously unrecognized general defect in N-glycan core fucosylation. PMID: 22745127
  2. study gives experimental proof that the product of the in silico identified Drosophila gene CG9620 serves as a functional GDP-fucose transporter PMID: 15530860
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families
TPT transporter family, SLC35C subfamily
Database Links

KEGG: dme:Dmel_CG9620

STRING: 7227.FBpp0081352

UniGene: Dm.31298

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