Product Details

Full Product Name

Rabbit anti-Sus scrofa (Pig) FUT1 Polyclonal antibody

Uniprot No.

Q29043

Target Names

FUT1

Alternative Names

FUT1Galactoside 2-alpha-L-fucosyltransferase 1 antibody; EC 2.4.1.344 antibody; Alpha(1,2)FT 1 antibody; Fucosyltransferase 1 antibody; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1 antibody

Raised in

Rabbit

Species Reactivity

Sus scrofa (Pig)

Immunogen

Recombinant Sus scrofa (Pig) FUT1 protein

Immunogen Species

Sus scrofa (Pig)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Target Background

Function

Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a.

Gene References into Functions

FUT1 expression levels and low FUT2 expression levels in the intestines of Sutai pigs affected FUT1 and FUT2 enzymes, the synthesis of type 2 H and type 1 H antigens, and E. coli F18 adhesion. Moreover, low FUT2 expression levels conferred resistance to E. coli F18. PMID: 26985939
Polymorphism of FUT1 and MUC4 associated with resistance to colibacteriosis was determined. PMID: 25318177
The 5'-flanking region of the FUT1 gene (-1150 to +50 bp) exhibited promoter activity and the -1150-bp to -849-bp region showed negative regulation of the gene. PMID: 24336113
Studied the beneficial effects of alpha (1,2)-fucosyltransferase (FUT1) M307 (A) on piglet survival on commercial farms. Piglet survival for individuals with the AA genotype was almost two-fold greater than for GG individuals. PMID: 23777352
The results indicated that Sutai pigs with the AA genotype in M307 of FUT1 gene have relatively strong general disease resistance ability in piglets. PMID: 21769474
The mutation at M307 in the FUT1 gene determines susceptibility of small intestinal epithelium to E. coli F18 adhesion in Sutai piglets. PMID: 21691705
FUT1 mutations might play a role in pig infection by multi-pathogens, and the AA may be a favourable genotype for increasing the resistance to disease. PMID: 21695432
Beneficial genotype of swine FUT1 gene governing resistance to E. coli F18 is associated with important economic traits PMID: 21869481
transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene PMID: 12672664
Genetic variability is assocated with reproductive traits. PMID: 16130473
Results showed that the genetic polymorphisms of the FUT1 locus were only detected in the 3 exotic pig breeds and indicated that FUT 1 gene and the type of breeds significantly affected total number born. PMID: 17284424
Results indicated that Chinese native pig breeds lack the genetic background, FUT1 genetic polymorphisms, on the resistance to ETEC F18 bacteria. PMID: 17855256
results showed that genetic polymorphisms of the FUT1 locus were only detected in western pig breeds & the Chinese Taihu, Huai & Lingao breeds; results indicated that Chinese native pig breeds lack genetic factors providing resistance to ETEC F18 bacteria PMID: 19134079

Hide All

Subcellular Location

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.

Protein Families

Glycosyltransferase 11 family

Database Links

KEGG: ssc:397138

STRING: 9823.ENSSSCP00000003400

UniGene: Ssc.242

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Code	CSB-PA643661XA01PI
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat

FUT1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background