FUT2 Antibody

Code CSB-PA612020XA01PI
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Product Details

Full Product Name
Rabbit anti-Sus scrofa (Pig) FUT2 Polyclonal antibody
Uniprot No.
Target Names
FUT2
Alternative Names
FUT2Galactoside 2-alpha-L-fucosyltransferase 2 antibody; EC 2.4.1.344 antibody; EC 2.4.1.69 antibody; Alpha(1,2)FT 2 antibody; Fucosyltransferase 2 antibody; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2 antibody
Raised in
Rabbit
Species Reactivity
Sus scrofa (Pig)
Immunogen
Recombinant Sus scrofa (Pig) FUT2 protein
Immunogen Species
Sus scrofa (Pig)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.
Gene References into Functions
  1. Association analysis revealed associations between rs345476947 polymorphism in the FUT2 gene and the number of newborn piglets and weaned piglets. PMID: 29892924
  2. FUT1 expression levels and low FUT2 expression levels in the intestines of Sutai pigs affected FUT1 and FUT2 enzymes, the synthesis of type 2 H and type 1 H antigens, and E. coli F18 adhesion. Moreover, low FUT2 expression levels conferred resistance to E. coli F18. PMID: 26985939
Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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