foxa4-a Antibody

Code CSB-PA339328XA01XBE
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Xenopus laevis (African clawed frog) foxa4-a Polyclonal antibody
Uniprot No.
Target Names
foxa4-a
Alternative Names
foxa4-aForkhead box protein A4-A antibody; FoxA4-A antibody; FoxA4a antibody; Fork head domain-related protein 1 antibody; xFD-1 antibody; Protein pintallavis antibody
Raised in
Rabbit
Species Reactivity
Xenopus laevis (African clawed frog)
Immunogen
Recombinant Xenopus laevis (African clawed frog) foxa4-a protein
Immunogen Species
Xenopus laevis (African clawed frog)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Transcriptional repressor involved in embryonic nervous system development. Plays a role in the induction and patterning of the anterior-posterior neural axis. Involved in the establishment of floor plate differentiation from neural plate cells during gastrulation. Binds the anf1 promoter sequence to restrict expression of anf1 to the anterior of the neural plate, thereby patterning the forebrain. Can bind to the HNF-3-alpha DNA target sequence. Cooperates with t/bra in a dose-dependent manner to specify dorsal mesoderm formation, including notochord. Binds to DNA via the target sequence 5'-[GA]TAAA[TC]A-3', with 5'-GTAAATA-3' being the preferred binding site.
Gene References into Functions
  1. FoxA4 prevents the respecification of dorsal midline precursors towards contiguous fates, inhibiting prechordal and paraxial mesoderm development in favour of the notochord. PMID: 25343614
Subcellular Location
Nucleus.
Tissue Specificity
During stages 8.5 to 10, expressed in the part of the dorsal mesoderm invaginating the dorsal blastopore lip (Spemann organizer), as a direct response to dorsal mesodermal induction. At stage 12 (mid-gastrulation), restricted to the dorsal midline in the
Database Links

KEGG: xla:394304

UniGene: Xl.441

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1