foxi1e Antibody

Code CSB-PA773654XA01XBE
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Product Details

Full Product Name
Rabbit anti-Xenopus laevis (African clawed frog) foxi1e Polyclonal antibody
Uniprot No.
Target Names
foxi1e
Alternative Names
foxi1e antibody; ema antibody; foxi1 antibody; foxi3Forkhead box protein I1-ema antibody; FoxI1-ema antibody; Ectodermally-expressed mesendoderm antagonist antibody; Xema antibody; FoxI3 antibody
Raised in
Rabbit
Species Reactivity
Xenopus laevis (African clawed frog)
Immunogen
Recombinant Xenopus laevis (African clawed frog) foxi1e protein
Immunogen Species
Xenopus laevis (African clawed frog)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcriptional activator. Activates ectoderm, in addition to inhibiting mesoderm and endoderm formation; required at the blastula stage for normal formation of both the central nervous system and epidermis, the two early derivatives of the ectoderm. In addition, also required to maintain the regional identity of the animal cells of the blastula, the cells that are precursors of ectodermal structures. Also plays a role in differential adhesion, which limits cell mixing as primary germ layers become specified.
Gene References into Functions
  1. Foxi2 thus acts as a link between the oocyte and the early pathway to ectoderm PMID: 22848601
  2. Xema is both necessary and sufficient for the inhibition of ectopic mesendoderm in the cells of the presumptive ectoderm PMID: 15901660
Subcellular Location
Nucleus.
Tissue Specificity
Expressed dynamically in a dorsal to ventral wave in the animal cap ectoderm in late blastula and gastrula stages. Expression is present in the cap in a salt and pepper arrangement which is maintained throughout early development. Expressed in lower level
Database Links

KEGG: xla:380059

UniGene: Xl.20089

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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