gabD Antibody

Code CSB-PA111164XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) gabD Polyclonal antibody
Uniprot No.
Target Names
gabD
Alternative Names
gabD antibody; b2661 antibody; JW2636 antibody; Succinate-semialdehyde dehydrogenase [NADP(+)] GabD antibody; SSDH antibody; EC 1.2.1.79 antibody; Glutarate-semialdehyde dehydrogenase antibody; EC 1.2.1.- antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) gabD protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. Thereby functions in a GABA degradation pathway that allows some E.coli strains to utilize GABA as a nitrogen source for growth. Also catalyzes the conversion of glutarate semialdehyde to glutarate, as part of a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
Gene References into Functions
  1. Data suggest that a deletion of three amino acids in gabD gene (SSADH) permits this enzyme to use NADP+. PMID: 20174634
  2. the crystal structure of EcSSADH, revealing that the catalytic loop of EcSSADH, unlike that of human SSADH, was presented. PMID: 20060383
Protein Families
Aldehyde dehydrogenase family
Database Links

KEGG: ecj:JW2636

STRING: 316407.85675513

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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