gag Antibody

Code CSB-PA318468XA01HQK
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Product Details

Full Product Name
Rabbit anti-Human T-cell leukemia virus 1 (strain Japan MT-2 subtype A) (HTLV-1) gag Polyclonal antibody
Uniprot No.
Target Names
gag
Alternative Names
gagGag polyprotein antibody; Pr53Gag) [Cleaved into: Matrix protein p19 antibody; MA); Capsid protein p24 antibody; CA); Nucleocapsid protein p15-gag antibody; NC-gag)] antibody
Raised in
Rabbit
Species Reactivity
Human T-cell leukemia virus 1 (strain Japan MT-2 subtype A) (HTLV-1)
Immunogen
Recombinant Human T-cell leukemia virus 1 (strain Japan MT-2 subtype A) (HTLV-1) gag protein
Immunogen Species
Human T-cell leukemia virus 1 (strain Japan MT-2 subtype A) (HTLV-1)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
The matrix domain targets Gag, Gag-Pro and Gag-Pro-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus.; Matrix protein.; Forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.; Binds strongly to viral nucleic acids and promote their aggregation. Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.
Subcellular Location
[Matrix protein p19]: Virion.; [Capsid protein p24]: Virion.; [Nucleocapsid protein p15-gag]: Virion.
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