gag Antibody

Datasheet

Code	CSB-PA357147XA01MCJ
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Product Details

Full Product Name

Rabbit anti-Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus) gag Polyclonal antibody

Uniprot No.

P07567

Target Names

gag

Alternative Names

gag antibody; Gag polyprotein antibody; Core polyprotein antibody; Pr78) [Cleaved into: Matrix protein p10; Phosphorylated protein pp24; Phosphorylated protein pp18; p12; Capsid protein p27; Nucleocapsid protein p14; p4] antibody

Raised in

Rabbit

Species Reactivity

Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)

Immunogen

Recombinant Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus) gag protein

Immunogen Species

Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Matrix protein.; Nucleocapsid protein.; capsid protein.

Gene References into Functions

In the in-vivo experiments, the Mason-Pfizer monkey virus matrix protein did not co-localize with lipid rafts. Therefore, the authors concluded that Mason-Pfizer monkey virus might adopt a different membrane binding mechanism than HIV-1. PMID: 27725181
Authors provide biochemical data confirming the critical role of the Mason-Pfizer monkey virus CA-NC spacer peptide-like domain in immature particle assembly, release, processing, and infectivity. PMID: 25275119
determined the solution structure of myristoylated Mason-Pfizer monkey virus matrix protein by NMR spectroscopy and provide a detailed insight into the molecular basis of its interaction with the plasma membrane PMID: 22863803
These data highlight the importance of a region containing alternating leucines and isoleucines within p12 for gag oligomerization. PMID: 17490704
Thus, basic amino acids in the M-PMV membrane-proximal surface of the matrix (MA) protein component of the Gag polyprotein define both cellular location and efficiency of virus release. PMID: 17596311

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Subcellular Location

[Matrix protein p10]: Virion.; [Capsid protein p27]: Virion.; [Nucleocapsid protein p14]: Virion.

Database Links

KEGG: vg:2746974

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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gag Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background