gag Antibody

Code CSB-PA339613XA01MAX
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Product Details

Full Product Name
Rabbit anti-Maedi visna virus (strain KV1772) (MVV) (Visna lentivirus) gag Polyclonal antibody
Uniprot No.
Target Names
gag
Alternative Names
gag antibody; Gag polyprotein [Cleaved into: Matrix protein p16; Capsid protein p25; Nucleocapsid protein p14] antibody
Raised in
Rabbit
Species Reactivity
Maedi visna virus (strain KV1772) (MVV) (Visna lentivirus)
Immunogen
Recombinant Maedi visna virus (strain KV1772) (MVV) (Visna lentivirus) gag protein
Immunogen Species
Maedi visna virus (strain KV1772) (MVV) (Visna lentivirus)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Mediates, with Gag-Pol polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence.; Targets the polyprotein to the plasma membrane.; Forms the core that encapsulates the genomic RNA-nucleocapsid complex in the virion.; Encapsulates and protects viral dimeric unspliced genomic RNA (gRNA). Binds these RNAs through its zinc fingers. Acts as a nucleic acid chaperone which is involved in rearrangement of nucleic acid secondary structure during gRNA retrotranscription. Also facilitates template switch leading to recombination.
Subcellular Location
[Matrix protein p16]: Virion.; [Capsid protein p25]: Virion.; [Nucleocapsid protein p14]: Virion.
Protein Families
Ovine/caprine lentivirus group gag polyprotein family
Database Links

KEGG: vg:1490012

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