gars-1 Antibody

Code CSB-PA604541XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans gars-1 Polyclonal antibody
Uniprot No.
Target Names
gars-1
Alternative Names
gars-1 antibody; grs-1 antibody; T10F2.1Glycine--tRNA ligase antibody; EC 6.1.1.14 antibody; Diadenosine tetraphosphate synthetase antibody; Ap4A synthetase antibody; EC 2.7.7.- antibody; Glycyl-tRNA synthetase antibody; GlyRS antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans gars-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.
Gene References into Functions
  1. A WHEP Domain Regulates the Dynamic Structure and Activity of Caenorhabditis elegans Glycyl-tRNA Synthetase. PMID: 27298321
Subcellular Location
Cytoplasm. Cell projection, axon. Secreted. Secreted, extracellular exosome.
Protein Families
Class-II aminoacyl-tRNA synthetase family
Database Links

KEGG: cel:CELE_T10F2.1

STRING: 6239.T10F2.1a

UniGene: Cel.17601

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