GB1 Antibody

Datasheet

Code	CSB-PA342989XA01DOA
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Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GB1 Polyclonal antibody

Uniprot No.

P49177

Target Names

GB1

Alternative Names

GB1 antibody; At4g34460 antibody; T4L20.40 antibody; Guanine nucleotide-binding protein subunit beta antibody; AGB1 antibody; transducin antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana GB1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression (e.g. lower xylose content in cell walls); involved in resistance to fungal pathogens such as Alternaria brassicicola and Fusarium oxysporum. Modulates root architecture (e.g. lateral root formation). Acts with XGL3 in the positive regulation of root waving and root skewing. Involved in the asymmetric division of zygote and specification of apical and basal cell lineages.

Gene References into Functions

AGB1 positively promotes hypocotyl elongation through repressing BBX21 activity. PMID: 28827171
AGB1 is mainly involved in the ionic toxicity component of salinity stress and plays roles in multiple processes of Na(+) homeostasis. PMID: 25808946
AGB1 is involved in the abscissic acid signaling pathway and drought tolerance in Arabidopsis. PMID: 25635681
Mutations in agb1 lead to an enlarged shoot apical meristem. AGB1 and RPK2 associate and synergistically regulate stem cell homeostasis. PMID: 25260844
At1g56590(AP-3micro) positively regulates the abscisic acid responses independently of AGB1 in seed germination, while AP-3micro does require AGB1 to regulate abscisic acid responses during post-germination growth. PMID: 24098050
Data indicate that G-protein beta subunit agb1/nph3 (a regulator of phototropism) double mutants showed no hypocotyl phototropism. PMID: 24486545
AGG3 binds AGB1 in vivo and in vitro. PMID: 21575088
Upon Pseudomonas syringae infection, AGB1 and AtRbohD and AtRbohF can function in the same pathway. In contrast, NADPH oxidase and heterotrimeric G proteins mediate different response pathways in response to Plectosphaerella cucumerina. PMID: 23441575
The Gbeta mutants were found to be hypersusceptible to spray inoculation with the bacterial pathogen Pseudomonas syringae. PMID: 23656333
The distribution of staining patterns in roots suggests that AGB1 and RFO1 restrict colonization of the vascular cylinder by F. oxysporum whereas EIR1 promotes colonization of root apices. PMID: 22894177
AGB1 residues critical for specific AGB1-mediated biological processes, including growth architecture, pathogen resistance, stomata-mediated leaf-air gas exchange, and possibly photosynthesis, were identified. PMID: 22570469
AGB1 affects Fusarium oxysporum-induced gene expression. PMID: 19054360
AGB1 is widely expressed throughout development in a complex manner. PMID: 17492287
AGB1 particupates in regulation of G protein-coupled inwardly rectifying K+ (GIRK) channels. PMID: 18541915
AGB1 appears to integrate pathogen-associated molecular pattern perception into downstream ROS production, and also to transmit the EF-Tu signal to the defense response, leading to reduced transformation by A. tumefaciens. PMID: 19129659

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Subcellular Location

Cell membrane. Cytoplasm. Nucleus.

Protein Families

WD repeat G protein beta family

Tissue Specificity

Expressed in seedlings (especially at the hypocotyl/root junction), roots, leaves (restricted to veins and guard cells), and flowers. Also present in hydathods. Expressed in guard cells, mesophyll tissue of cotyledons, trichomes and whole siliques, but no

Database Links

KEGG: ath:AT4G34460

STRING: 3702.AT4G34460.1

UniGene: At.22855

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GB1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background