gcy-36 Antibody

Code CSB-PA732256XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans gcy-36 Polyclonal antibody
Uniprot No.
Target Names
gcy-36
Alternative Names
gcy-36 antibody; C46E1.2Soluble guanylate cyclase gcy-36 antibody; EC 4.6.1.2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans gcy-36 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a central role in social feeding behavior by synthesizing 3',5'-cyclic guanosine monophosphate (cGMP) from GTP. Oxygen, which probably binds to its heme-binding sites, may regulate social behavior by modulating its activity. cGMP is a common second messenger in sensory transduction and is implicated in oxygen sensation. Indeed, C.elegans exhibits a strong behavioral preference for 5-12% oxygen, avoiding higher and lower oxygen levels; a higher level of oxygen inducing a naturally polymorphic social feeding behavior. Involved in avoidance of hyperoxia and for oxygen-induced aggregation and bordering, probably by mediating oxygen sensing in URX, AQR and PQR sensory neurons.
Subcellular Location
Cytoplasm.
Protein Families
Adenylyl cyclase class-4/guanylyl cyclase family
Tissue Specificity
Expressed in URX, AQR and PQR neurons.
Database Links

KEGG: cel:CELE_C46E1.2

STRING: 6239.C46E1.2

UniGene: Cel.9117

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