GDF6A Antibody

Code CSB-PA309201XA01DIL
Product Type Polyclonal Antibody
Uniprot No. P85857
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) GDF6A protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Growth/differentiation factor 6-A (GDF-6-A) (Growth differentiation factor 6A) (Protein radar) gdf6a radar rdr
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names gdf6a
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Growth factor that controls proliferation and cellular differentiation in the retina. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Functions maternally in dorsal/ventral patterning to induce the expression of the zygotic bmp2b and bmp4 genes and ventralize embryos. Zygotic expression does not appear to regulate axis specification, but instead functions to establish the integrity of the axial vessels during embryonic development. May be involved in maintaining the identity of cells of the dorsal-most neural tube and of at least a subset of neural crest cells.
Subcellular Location Secreted
Protein Families TGF-beta family
Tissue Specificity First expressed in late gastrula stage embryos (9.5 hours post fertilization (hpf)) in anterior neuroectoderm corresponding to the future dorsal part of the brain. Shortly after tailbud formation (11 hpf), expression expands to the entire neural region an
Database Links

KEGG: dre:566470

STRING: 7955.ENSDARP00000069999

UniGene: Dr.16432

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