gei-17 Antibody

Code CSB-PA842438XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans gei-17 Polyclonal antibody
Uniprot No.
Target Names
gei-17
Alternative Names
gei-17 antibody; W10D5.3E3 SUMO-protein ligase gei-17 antibody; EC 2.3.2.- antibody; E3 SUMO-protein transferase gei-17 antibody; Gex-3-interacting protein 17 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans gei-17 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Functions as an E3-type smo-1 ligase. Mediates smo-1 conjugation to air-2 in vitro and is required for proper chromosome alignment. In the early embryo, specifically suppresses checkpoint activation in response to DNA damage, maybe by promoting mus-101 sumoylation. In embryos, plays a role in determining telomere localization in the nucleus.
Gene References into Functions
  1. SUMO E3 ligase GEI-17/PIAS is required for KLP-19 recruitment to the multiprotein ring complex regulating chromosome congression during oocyte meiosis. PMID: 27939944
Protein Families
PIAS family
Database Links

KEGG: cel:CELE_W10D5.3

STRING: 6239.W10D5.3c.3

UniGene: Cel.5457

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