GG1 Antibody

Code CSB-PA592717XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GG1 Polyclonal antibody
Uniprot No.
Target Names
GG1
Alternative Names
GG1 antibody; AGG1 antibody; At3g63420 antibody; MAA21.50 antibody; Guanine nucleotide-binding protein subunit gamma 1 antibody; Ggamma-subunit 1 antibody; Heterotrimeric G protein gamma-subunit 1 antibody; AtAGG1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana GG1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Involved in the abscisic acid (ABA) and ethylene signaling pathways. Regulates acropetal transport of auxin (IAA) in roots and hypocotyls, and thus modulates root architecture (e.g. lateral root formation). The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression; involved in resistance to fungal pathogens such as Alternaria brassicicola, Plectosphaerella cucumerina and Fusarium oxysporum.
Gene References into Functions
  1. The fact that AGG1 and AGG2 are functionally interchangeable in some pathways implies that, at least for those pathways, signaling specificity resides in the distinctive spatiotemporal expression patterns exhibited by each gamma subunit. PMID: 23520518
  2. AGG1, AGG2 and AGB1 control the immune responses and the regulation of cell wall composition. PMID: 21980142
  3. Posttranslational modification of AGG1 is required for plasma membrane targeting. PMID: 17220359
Subcellular Location
Cell membrane. Golgi apparatus membrane. Golgi apparatus, trans-Golgi network membrane. Cytoplasm.
Tissue Specificity
Mostly expressed in seedlings (especially at the hypocotyl/root junction), young cauline leaves, open flowers, and floral stems, and, to a lower extent, in roots (restricted to the stele), rosette leaves (restricted to veins), siliques, and unopened flora
Database Links

KEGG: ath:AT3G63420

STRING: 3702.AT3G63420.1

UniGene: At.5190

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