gt Antibody

Datasheet

Code	CSB-PA340119XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) gt Polyclonal antibody

Uniprot No.

P39572

Target Names

Alternative Names

gt antibody; CG7952 antibody; Protein giant antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) gt protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Represses the expression of both the krueppel and knirps segmentation gap genes. Binds, in vitro, to the krueppel regulatory elements CD1 and CD2. It is required in the early embryo for the development of portions of the head and abdomen.

Gene References into Functions

there are two phases of transcriptional regulation for the gap gene giant in Drosophila PMID: 26806702
two polycomb response elements-containing regions at the Polycomb-group proteins target gene, giant, one at the promoter, and another approximately 6 kb upstream. PMID: 24170735
Results showed Gt repression roles in the regulation of two groups of partially overlapping stripes and that Gt morphogen activity is part of the mechanism responsible for the differential positioning of these stripes borders. PMID: 20925117
gt likely controls ecdysone production indirectly by contributing the peptidergic phenotype of the PTTH-producing neurons in the embryo PMID: 20816678
The Drosophila gap gene giant has an anterior segment identity function mediated through disconnected and teashirt. PMID: 18493063

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Subcellular Location

Nucleus.

Protein Families

BZIP family

Database Links

KEGG: dme:Dmel_CG7952

STRING: 7227.FBpp0070444

UniGene: Dm.5740

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gt Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background