gsp-2 Antibody

Code CSB-PA343753XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans gsp-2 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
gsp-2 antibody; Ce-glc-7beta antibody; CeGLC-7beta antibody; glc-7 antibody; F56C9.1 antibody; Serine/threonine-protein phosphatase PP1-beta antibody; EC antibody; CeGLC-7-beta antibody; Glc seven-like phosphatase 2 antibody
Raised in
Species Reactivity
Caenorhabditis elegans
Recombinant Caenorhabditis elegans gsp-2 protein
Immunogen Species
Caenorhabditis elegans
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Serine/threonine-protein phosphatase essential for chromosomal dynamics during meiosis and mitosis. During meiosis, promotes chromosomal cohesion and germline immortality via a small RNA-mediated genome silencing pathway. Antagonizes the function of air-2 kinase during meiosis I and mitosis to promote chromatid cohesion and spindle attachment. Dephosphorylates histone H3 at 'Ser-10' (Probable). Dephosphorylates histone H3 at 'Thr-3' (Probable). Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Promotes small RNA-mediated genome silencing over multiple generations. Essential for embryogenesis.
Gene References into Functions
  1. LAB-1 is required to target GSP-2 to early meiotic nuclei. PMID: 22927794
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
PPP phosphatase family, PP-1 subfamily
Tissue Specificity
Expressed in gonads, nervous system, intestine and muscles.
Database Links

KEGG: cel:CELE_F56C9.1

STRING: 6239.F56C9.1.1

UniGene: Cel.24408

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