glgC Antibody

Code CSB-PA358879XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) glgC Polyclonal antibody
Uniprot No.
Target Names
glgC
Alternative Names
glgC antibody; b3430 antibody; JW3393Glucose-1-phosphate adenylyltransferase antibody; EC 2.7.7.27 antibody; ADP-glucose pyrophosphorylase antibody; ADPGlc PPase antibody; ADP-glucose synthase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) glgC protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
Gene References into Functions
  1. A model has been proposed in which the energy reporters regulate ADP-glucose pyrophosphorylase catalytic activity by intra-protomer interactions and inter-protomer crosstalk, with a sensory motif and two regulatory loops playing a prominent role. PMID: 27545622
  2. Using computational studies, site-directed mutagenesis, and kinetic characterization, we found a critical region for transmitting the allosteric signal in the Escherichia coli ADP-glucose pyrophosphorylase PMID: 25620658
  3. Structural role of N-terminus in allosteric regulation of ADPglucose pyrophosphorylase was studied. PMID: 16530732
  4. First detailed characterization of the sugar phosphate site and the three-dimensional structure of ADP-glucose pyrophosphorylase. PMID: 17079236
  5. ADP-glucose pyrophosphorylase with a pentapeptide insertion between Leu(102) and Pro(103) was catalytically competent but insensitive to activation. PMID: 17496097

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Protein Families
Bacterial/plant glucose-1-phosphate adenylyltransferase family
Database Links
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