glod-4 Antibody

Code CSB-PA937832XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans glod-4 Polyclonal antibody
Uniprot No.
Target Names
glod-4
Alternative Names
glod-4 antibody; tag-73 antibody; C16C10.10 antibody; Glyoxalase 1 antibody; CeGly antibody; Glyoxalase domain-containing protein 4 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans glod-4 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Thought to act as a glyoxalase. May remove methylglyoxal from mitochondrial proteins. Has roles in reducing oxidative stress and increasing lifespan.
Gene References into Functions
  1. Data suggest that, under high glucose conditions, mitochondria-mediated oxidative stress and glycation are downstream targets of ins-7; this impairs neuronal system function and longevity via non-neuronal/neuronal crosstalk by affecting sod-3 and glod-4. (ins-7 = insulin related Probable insulin-like peptide beta-type 4; sod-3 = mitochondrial Mn+2 superoxide dismutase; glod-4 = glyoxalase 1) PMID: 27776915
Protein Families
Glyoxalase I family
Tissue Specificity
Expressed in the following tissues in both larvae and adults: pharynx, pharyngeal-intestinal valve, intestine, anal sphincter, vulval muscle, seam cells and the nervous system.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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