GLUTRBP Antibody

Code CSB-PA123989XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GLUTRBP Polyclonal antibody
Uniprot No.
Target Names
GLUTRBP
Alternative Names
GLUTRBP antibody; PGR7 antibody; At3g21200 antibody; MXL8.5Glutamyl-tRNA reductase-binding protein antibody; chloroplastic antibody; AtGluTRBP antibody; GluTR-binding protein antibody; Protein PROTON GRADIENT REGULATION 7 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana GLUTRBP protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in the regulation of glutamyl-tRNA reductase (GluTR) which is important for the synthesis and distribution of 5-aminolevulinate, a precursor in heme and chlorophyll biosynthesis. Stimulates GluTR activity and regulates glutamate-1-semialdehyde release. May play a role in heme metabolism. Necessary for efficient photosynthetic electron transport in chloroplasts.
Gene References into Functions
  1. ClpS1 and the ClpC1 chaperone as well as the GluTR-binding protein (GBP) interact with the N terminus of GluTR Loss-of function mutants of ClpR2 and ClpC1 proteins show increased GluTR stability, whereas absence of GBP results in decreased GluTR stability. Thus, the Clp protease system and GBP contribute to GluTR accumulation levels, and thereby the rate-limiting ALA synthesis.[GBP] PMID: 26884485
  2. A ternary complex composed of the C-terminal tetratricopepetide-repeat domain of FLU, GBP, and GluTR and a biological role of the ternary complex for the regulation of plant GluTR is reported. [GBP] PMID: 26794057
  3. GluTRBP is bound to the thylakoid membrane. Reduction of GluTRBP contents causes heme deficiency. PMID: 22180625
  4. Study identified PGR7 as a novel, conserved nuclear gene that is necessary for efficient photosynthetic electron transport in chloroplasts of Arabidopsis. PMID: 20657737
Subcellular Location
Plastid, chloroplast stroma.
Database Links

KEGG: ath:AT3G21200

STRING: 3702.AT3G21200.1

UniGene: At.70384

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