GLYR1 Antibody

Code CSB-PA786154XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GLYR1 Polyclonal antibody
Uniprot No.
Target Names
GLYR1
Alternative Names
GLYR1 antibody; GR1 antibody; At3g25530 antibody; MWL2.18 antibody; Glyoxylate/succinic semialdehyde reductase 1 antibody; AtGLYR1 antibody; AtGR1 antibody; SSA reductase 1 antibody; EC 1.1.1.79 antibody; EC 1.1.1.n11 antibody; Gamma-hydroxybutyrate dehydrogenase antibody; AtGHBDH antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana GLYR1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the NADPH-dependent reduction of glyoxylate to glycolate as well as succinic semialdehyde (SSA) to gamma-hydroxybutyrate in vitro. May function in redox homeostasis and play a role in oxidative stress tolerance by detoxifying glyoxylate and SSA generated in glycolate metabolism and GABA metabolism, respectively.
Gene References into Functions
  1. Sequence and activity comparisons indicated that AtGLYR1 and AtGLYR2 possess structural features that are absent in Arabidopsis hydroxypyruvate reductases and probably account for their stronger preference for glyoxylate over hydroxypyruvate. PMID: 24076009
  2. These results define the cytosol as the intracellular location of GLYR1. PMID: 22309191
  3. GR1 and GR2 are involved in the regulation of Succinic semialdehyde detoxification in plants. [glyoxylate reductase 1] [AtGR1] PMID: 18495640
Subcellular Location
Cytoplasm, cytosol. Note=According to PubMed:22309191, GLYR1 does not localize in the peroxisome as initially described in PubMed:18495639.
Protein Families
3-hydroxyisobutyrate dehydrogenase family, NP60 subfamily
Database Links

KEGG: ath:AT3G25530

STRING: 3702.AT3G25530.1

UniGene: At.21370

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