GPER1 Antibody

Code CSB-PA224751XA01DIL
Product Type Polyclonal Antibody
Uniprot No. B3G515
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) GPER1 protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias G-protein coupled estrogen receptor 1 (G protein-coupled estrogen receptor 1) (G-protein coupled receptor 30) gper1
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names gper1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Membrane G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Plays a role in the embryonic development of sensory and motor neurons. Specifically induces apoptosis and reduces proliferation of brain cells. Involved in maintenance of meiotic arrest in oocytes.
Subcellular Location Nucleus, Cytoplasm, perinuclear region, Cytoplasm, Cytoplasm, cytoskeleton, Cytoplasmic vesicle membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein, Basolateral cell membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane, Multi-pass membrane protein, Early endosome, Recycling endosome, Golgi apparatus, trans-Golgi network, Golgi apparatus membrane, Multi-pass membrane protein, Cell projection, dendrite, Cell projection, dendritic spine membrane, Multi-pass membrane protein, Cell projection, axon, Cell junction, synapse, postsynaptic cell membrane, postsynaptic density, Mitochondrion membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family
Tissue Specificity Expressed in brain regions that are known to control reproduction and sex behavior. Expressed in ovary, muscle and intestine. Expressed in early germ cells of the testis, including the spermatogonia, spermatocytes, and somatic cells such as Sertoli cells.
Database Links

KEGG: dre:565271

STRING: 7955.ENSDARP00000070486

UniGene: Dr.148317

Pathway Estrogen signaling pathway

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