GRXS17 Antibody

Code CSB-PA951086XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GRXS17 Polyclonal antibody
Uniprot No.
Target Names
GRXS17
Alternative Names
GRXS17 antibody; At4g04950 antibody; T1J1.6Monothiol glutaredoxin-S17 antibody; AtGrxS17 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana GRXS17 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May only reduce GSH-thiol disulfides, but not protein disulfides (Probable). Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins. The GRXS17-BOLA2 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster.
Gene References into Functions
  1. Glutaredoxin grxs17 loss-of-function mutants showed some degree of hypersensitivity to DNA damage and elevated expression of DNA damage marker genes. PMID: 27503603
  2. GRXS17 is an ubiquitination target of RGLG3 and is ubiquitinated and degraded in a proteasome-dependent manner by RGLG3 and RGLG4. PMID: 27497447
  3. Ectopic expression of AtGRXS17 from Arabidopsis thaliana in tomato plants minimized photo-oxidation of chlorophyll and reduced oxidative damage of cell membrane systems under heat stress PMID: 22762155
  4. Arabidopsis monothiol glutaredoxin, AtGRXS17, is critical for temperature-dependent postembryonic growth and development via modulating auxin response. PMID: 21515673
Subcellular Location
Cytoplasm.
Protein Families
Glutaredoxin family, CGFS subfamily
Database Links

KEGG: ath:AT4G04950

STRING: 3702.AT4G04950.1

UniGene: At.4053

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