MSB3 Antibody

Code CSB-PA343742XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MSB3 Polyclonal antibody
Uniprot No.
Target Names
MSB3
Alternative Names
MSB3 antibody; GYP3 antibody; YNL293W antibody; N0470 antibody; GTPase-activating protein GYP3 antibody; Multicopy suppressor of bud emergence 3 antibody; Protein MSB3 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MSB3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Regulates exocytosis by functioning as a GAP for SEC4. Stimulates specifically the GTPase activity of YPT6. Also required for efficient polarization of the actin patches.
Gene References into Functions
  1. BLOC-1 is both a Vps21 effector and an adapter for its GAP Msb3. PMID: 23547030
  2. Msb3 can act on multiple substrates in vivo at both ends of a trafficking pathway PMID: 22593206
  3. The results suggest a possible involvement of Msb3p in calcineurin-mediated signalling. PMID: 20872164
Subcellular Location
Cytoplasm. Bud. Bud neck. Note=Localizes to the presumptive bud site, the bud tip and the mother-bud neck.
Database Links

KEGG: sce:YNL293W

STRING: 4932.YNL293W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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