His3 Antibody

Code CSB-PA365735XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) His3; Polyclonal antibody
Uniprot No.
Target Names
His3;
Alternative Names
His3; antibody; His3:CG31613 antibody; CG31613; antibody; His3:CG33803 antibody; CG33803; antibody; His3:CG33806 antibody; CG33806; antibody; His3:CG33809 antibody; CG33809; antibody; His3:CG33812 antibody; CG33812; antibody; His3:CG33815 antibody; CG33815; antibody; His3:CG33818 antibody; CG33818; antibody; His3:CG33821 antibody; CG33821; antibody; His3:CG33824 antibody; CG33824; antibody; His3:CG33827 antibody; CG33827; antibody; His3:CG33830 antibody; CG33830; antibody; His3:CG33833 antibody; CG33833; antibody; His3:CG33836 antibody; CG33836; antibody; His3:CG33839 antibody; CG33839; antibody; His3:CG33842 antibody; CG33842; antibody; His3:CG33845 antibody; CG33845; antibody; His3:CG33848 antibody; CG33848; antibody; His3:CG33851 antibody; CG33851; antibody; His3:CG33854 antibody; CG33854; antibody; His3:CG33857 antibody; CG33857; antibody; His3:CG33860 antibody; CG33860; antibody; His3:CG33863 antibody; CG33863; antibody; His3:CG33866 antibody; CG33866 antibody; Histone H3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) His3 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene References into Functions
  1. Acetylation of histone H3 lysine 23 is localized to promoters and correlates with endogenous ecdysone induced gene activation. PMID: 22808194
  2. In Su(var)3-9 null mutants, H3-K9 methylation at chromocentre heterochromatin is strongly reduced, indicating that SU(VAR)3-9 is the major heterochromatin-specific HMTase in Drosophila. PMID: 11867540
  3. Phosphorylation of H3 is linked to transcription and can be modulated by the structure of the promoter. PMID: 12514098
Subcellular Location
Nucleus. Chromosome.
Protein Families
Histone H3 family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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