HAA1 Antibody

1. HRR25 lead to reduced Haa1 phosphorylation and increased expression of Haa1 target genes and that Hrr25 interacts with Haa1. PMID: 28432100
2. In response to acetic acid stress, marked differences were found in the regulons controlled by CgHaa1 and by its S. cerevisiae ScHaa1 ortholog, demonstrating a clear divergent evolution of the two regulatory networks. The results gathered in this study significantly advance the understanding of the molecular mechanisms underlying the success of C. glabrata as a vaginal colonizer. PMID: 27815348
3. These results suggest that regulation of the subcellular localization of Haa1, together with alteration of its phosphorylation status, mediates the adaptation to lactic acid stress in yeast. PMID: 24682296
4. This study demonstrated that the S. cerevisae transcription factor Haa1 requires the DNA sequence 5'-(G/C)(A/C)GG(G/C)G-3' in the promoter region of acetic-acid-responsive genes to activate their expression. PMID: 21586585
5. Data suggest that the role of both HAA1 and HRK1 in providing protection against acetic acid is, at least partially, related with their involvement in the reduction of intracellular acetate concentration. PMID: 20955010
6. Haa1p is required for a more rapid adaptation of a yeast cell population to several weak acid food preservatives. PMID: 16176797

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KEGG: sce:YPR008W

STRING: 4932.YPR008W