ham Antibody

Code CSB-PA808512XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) ham Polyclonal antibody
Uniprot No.
Target Names
ham
Alternative Names
ham antibody; CG31753 antibody; Transcription factor hamlet antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) ham protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor that plays a crucial role in external sensory organ (ESO) that elaborates from a single precursor cell (ESOP cell). Mediates the differentiation of lineage branch that generates the internal 'ES' and 'th' cells (external sensory neuron and thecogen cells, respectively) from the IIIB cell. Its absence leads to re-specification of IIIB daughter cells into external tormagen cells (tr cells), or internal multidendritic neurons (MD cells). One of its role in the development of the ESO lineage is to modulate the activity of Notch and PAX2 signals.
Gene References into Functions
  1. analysis of physical and functional interactions between Drosophila homologue of Swc6/p18Hamlet subunit of the SWR1/SRCAP chromatin-remodeling complex with the DNA repair/transcription factor TFIIH PMID: 22865882
  2. This study demonistrated that Ham modifies cellular responses to these iteratively used Notch signals in a context-dependent manner, and controls odorant receptor gene choice and ORN axon targeting specificity. PMID: 22197833
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in the developing peripheral nervous system (PNS). Expressed in the ventral patch in the cephalic region of the embryo from stage 5, and continues in cephalic region through stage 15. Expressed in the developing PNS from stage 11 to 15, with a t
Database Links
CUSABIO guaranteed quality
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