hbl-1 Antibody

1. This study demonistrated that convergent regulation of hbl-1 expression defines a genetic mechanism that patterns activity-dependent synaptic remodeling across cell types and across developmental time. PMID: 22325199
2. hbl-1 can also modulate the dauer formation decision in a complex manner PMID: 20980238
3. Given that SYM-1 is a protein secreted from hypodermal cells to the surrounding cuticle, we propose that the adult-specific cuticular structures may be under the temporal control of HBL-1 through regulation of sym-1 transcription. PMID: 19923914
4. propose that hunchback, Ikaros, and the HIL genes arose from a common ancestor that was present prior to the divergence of protostomes and deuterostomes PMID: 20026024
5. hbl-1/lin-57 is regulated by let-7 PMID: 12737799
6. Here we show that hbl-1, the C. elegans hunchback ortholog, also controls temporal patterning. PMID: 12737800
7. Temporal regulator hbl-1, the Caenorhabditis elegans ortholog of hunchback, interacts with puf-9; this regulation is dependent on a region of the hbl-1 3'UTR that contains putative Puf family binding sites. PMID: 17412319
8. One of let-7's targets, HBL-1, inhibits the transcription of let-7 in specific tissues until the L3 stage via a negative feedback loop. PMID: 19627983

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KEGG: cel:CELE_F13D11.2

STRING: 6239.F13D11.2a

UniGene: Cel.5045