HDA18 Antibody

Datasheet

Code	CSB-PA818607XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) HDA18 Polyclonal antibody

Uniprot No.

Q8LRK8

Target Names

HDA18

Alternative Names

HDA18 antibody; At5g61070 antibody; MAF19.8 antibody; Histone deacetylase 18 antibody; EC 3.5.1.98 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana HDA18 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (Probable). Histone deacetylases act via the formation of large multiprotein complexes (Probable). Required for appropriate cellular patterning in the root epidermis. Involved in the differentiation of hair and non-hair cells in the root epidermis. Is not directly involved in the regulation of the expression of pattern genes. Regulates the transcription of certain kinase genes, which are components of a positional information relay system, by changing their histone acetylation status.

Gene References into Functions

HDA18 affects cellular patterning in Arabidopsis root epidermis. The HDA18 protein physically interacted with histones related to a specific group of kinase genes, which are components of a positional information relay system. PMID: 23362208

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

Histone deacetylase family, HD type 2 subfamily

Tissue Specificity

Expressed in roots, stems, young rosette leaves, flowers and siliques.

Database Links

KEGG: ath:AT5G61070

STRING: 3702.AT5G61070.1

UniGene: At.29127

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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HDA18 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background